科研成果

[1] Xu BM, Liu CK, Sun HY, Wang XQ, Huang F. Oil-in-water Pickering emulsions using a protein nano-ring as high-grade emulsifiers. Colloids and Surfaces B-Biointerfaces. 2020, 187. doi: 10.1016/j.colsurfb.2019.110646

[2] Wang XQ, Li SX, Wang C, Mujuni CJ, Yue TT, Huang F. Supramolecular Construction of Biohybrid Nanozymes Based on the Molecular Chaperone GroEL as a Promiscuous Scaffold. Acs Biomaterials Science & Engineering. 2020, 6(2): 833-841. doi: 10.1021/acsbiomaterials.9b00997

[3] Ma XQ, Wang XJ, Chen Q, He H, Sun YX, Liu H, Wang YA, Qu JB, Huang F. Glycosaminoglycan/gold nanocluster hybrid nanoparticles as a new sensing platform: Metastatic potential assessment of cancer cells. Carbohydrate Polymers. 2020, 230. doi: 10.1016/j.carbpol.2019.115654

[4] Li SX, Yan ZS, Huang F, Zhang XR, Yue TT. How a lipid bilayer membrane responds to an oscillating nanoparticle: Promoted membrane undulation and directional wave propagation. Colloids and Surfaces B-Biointerfaces. 2020, 187. doi: 10.1016/j.colsurfb.2019.110651

[5] Li SX, Lv RJ, Yan ZS, Huang F, Zhang XR, Chen GJ, Yue TT. Design of Alanine-Rich Short Peptides as a Green Alternative of Gas Hydrate Inhibitors: Dual Methyl Group Docking for Efficient Adsorption on the Surface of Gas Hydrates. Acs Sustainable Chemistry & Engineering. 2020, 8(10): 4256-4266. doi: 10.1021/acssuschemeng.9b07701

[6] He H, Shi XJ, Wang JY, Wang XJ, Wang Q, Yu DY, Ge BS, Zhang XD, Huang F. Reactive Oxygen Species-Induced Aggregation of Nanozymes for Neuron Injury. Acs Applied Materials & Interfaces. 2020, 12(1): 209-216. doi: 10.1021/acsami.9b17509

[7] Yu XX, Tian NN, Huang F, Huang X, Liu CL, Gao S, Yang Z, Wu YN. Evaluating the role of ionic liquids (ILs) in the crystallization of lysozyme. Journal of Molecular Liquids. 2019, 296. doi: 10.1016/j.molliq.2019.112018

[8] Yu DY, Lan JX, Khan NU, Li Q, Xu FX, Huang GH, Xu H, Huang F. The in vitro synergistic denaturation effect of heat and surfactant on photosystem I isolated from Arthrospira Platensis. Photosynthesis Research. 2019, 141(2): 229-243. doi: 10.1007/s11120-019-00623-y

[9] Xu Y, Li SX, Yan ZS, Ge BS, Huang F, Yue TT. Revealing Cooperation between Knotted Conformation and Dimerization in Protein Stabilization by Molecular Dynamics Simulations. Journal of Physical Chemistry Letters. 2019, 10(19): 5815-5822. doi: 10.1021/acs.jpclett.9b02209

[10] Xu BM, Liu CK, Sun HY, Wang XQ, Huang F. Highly Surface-Active Chaperonin Nanobarrels for Oil-in-Water Pickering Emulsions and Delivery of Lipophilic Compounds. Journal of Agricultural and Food Chemistry. 2019, 67(36): 10155-10164. doi: 10.1021/acs.jafc.9b02379

[11] Wang YN, Wang XJ, Ma XQ, Chen Q, He H, Nau WM, Huang F. Coassembly of Gold Nanoclusters with Nucleic Acids: Sensing, Bioimaging, and Gene Transfection. Particle & Particle Systems Characterization. 2019, 36(10). doi: 10.1002/ppsc.201900281

[12] Wang XJ, Qi C, Zhang ZY, He H, Ma XQ, Liu ZZ, Ge BS, Huang F. Novel Enteromorpha Prolifera based carbon dots: Probing the radical scavenging of natural phenolic compounds. Colloids and Surfaces B-Biointerfaces. 2019, 174: 161-167. doi: 10.1016/j.colsurfb.2018.11.019

[13] Wang XJ, Liu ZZ, Chen Q, Wang XQ, Huang F. Interactions between Graphene Materials and Proteins. Progress in Chemistry. 2019, 31(2-3): 236-244. doi: 10.7536/pc180445

[14] Li SX, Yang ZS, Luo Z, Xu Y, Huang F, Zhang XR, Yi X, Yue TT. Mechanics of the Formation, Interaction, and Evolution of Membrane Tubular Structures. Biophysical Journal. 2019, 116(5): 884-892. doi: 10.1016/j.bpj.2019.01.032

[15] Li SX, Yan ZS, Luo Z, Xu Y, Huang F, Hu GQ, Zhang XR, Yue TT. Directional and Rotational Motions of Nanoparticles on Plasma Membranes as Local Probes of Surface Tension Propagation. Langmuir. 2019, 35(15): 5333-5341. doi: 10.1021/acs.langmuir.9b00225

[16] Li SX, Lv RJ, Wu YN, Huang F, Zhang XR, Yue TT. Size-, Aggregation-, and Oxidization-Dependent Perturbation of Methane Hydrate by Graphene Nanosheets Revealed by Molecular Dynamics Simulations. Journal of Physical Chemistry C. 2019, 123(20): 13154-13166. doi: 10.1021/acs.jpcc.9b02659

[17] Huang HH, Ge BS, Zhang S, Li JQ, Sun CH, Yue TT, Huang F. Using Fluorescence Quenching Titration to Determine the Orientation of a Model Transmembrane Protein in Mimic Membranes. Materials. 2019, 12(3). doi: 10.3390/ma12030349

[18] Huang HH, Ge BS, Sun CH, Zhang S, Huang F. Membrane curvature affects the stability and folding kinetics of bacteriorhodopsin. Process Biochemistry. 2019, 76: 111-117. doi: 10.1016/j.procbio.2018.10.002

[19] Ge BS, He JY, Zhang Q, Wei Y, Xi LJ, Khan NU, Huang F. Evaluation of various sulfides for enhanced photobiological H-2 production by a dual-species co-culture system of Chlamydomonas reinhardtii and Thiomonas intermedia. Process Biochemistry. 2019, 82: 110-116. doi: 10.1016/j.procbio.2019.03.028

[20] Yu XX, Wu YN, Huang F, Ulrich J, Wang JK. Purification of Recombinant L-Asparaginase II Using Solvent-Freeze-Out Technology. Chemical Engineering & Technology. 2018, 41(6): 1080-1085. doi: 10.1002/ceat.201700569

[21] Xu Y, Li SX, Yan ZS, Luo Z, Ren H, Ge BS, Huang F, Yue TT. Stabilizing Effect of Inherent Knots on Proteins Revealed by Molecular Dynamics Simulations. Biophysical Journal. 2018, 115(9): 1681-1689. doi: 10.1016/j.bpj.2018.09.015

[22] Xu Y, Li SX, Luo Z, Ren H, Zhang XR, Huang F, Zuo YY, Yue TT. Role of Lipid Coating in the Transport of Nanodroplets across the Pulmonary Surfactant Layer Revealed by Molecular Dynamics Simulations. Langmuir. 2018, 34(30): 9054-9063. doi: 10.1021/acs.langmuir.8b01547

[23] Wang XQ, Wang C, Xu BM, Wei JT, Xiao Y, Huang F. Adsorption of intrinsically disordered barnacle adhesive proteins on silica surface. Applied Surface Science. 2018, 427: 942-949. doi: 10.1016/j.apsusc.2017.08.108

[24] Wang XQ, Chen H, Lu XW, Chi HX, Li SX, Huang F. Probing the interaction mechanisms between transmembrane peptides and the chaperonin GroEL with fluorescence anisotropy. Spectrochimica Acta Part a-Molecular and Biomolecular Spectroscopy. 2018, 194: 1-7. doi: 10.1016/j.saa.2017.12.071

[25] Song YZ, Ge BS, Lao J, Wang ZC, Yang B, Wang XJ, He H, Li JQ, Huang F. Regulation of the Oligomeric Status of CCR3 with Binding Ligands Revealed by Single-Molecule Fluorescence Imaging. Biochemistry. 2018, 57(5): 852-860. doi: 10.1021/acs.biochem.7b00676

[26] Luo Z, Li SX, Xu Y, Yan ZS, Huang F, Yue TT. The role of nanoparticle shape in translocation across the pulmonary surfactant layer revealed by molecular dynamics simulations. Environmental Science-Nano. 2018, 5(8): 1921-1932. doi: 10.1039/c8en00521d

[27] Luo Z, Li SX, Xu Y, Ren H, Zhang XR, Hu GQ, Huang F, Yue TT. Extracting pulmonary surfactants to form inverse micelles on suspended graphene nanosheets. Environmental Science-Nano. 2018, 5(1): 130-140. doi: 10.1039/c7en00843k

[28] Khan NU, He H, Wang XJ, Ge BS, Wang Q, Liu X, Lao J, Wang YA, Li JQ, Wang ZC, Zhou ST, Huang F. A two-color fluorescence enhanced dot-blot assay for revealing co-operative expression of chemokine receptors in cells. Chemical Communications. 2018, 54(7): 778-781. doi: 10.1039/c7cc08167g

[29] Khan NU, Feng ZZ, He H, Wang Q, Liu X, Li S, Shi XJ, Wang XJ, Ge BS, Huang F. A facile plasmonic silver needle for fluorescence-enhanced detection of tumor markers. Analytica Chimica Acta. 2018, 1040: 120-127. doi: 10.1016/j.aca.2018.07.071

[30] Jacob MH, D'Souza RN, Schwarzlose T, Wang XJ, Huang F, Haas E, Nau WM. Method-Unifying View of Loop-Formation Kinetics in Peptide and Protein Folding. Journal of Physical Chemistry B. 2018, 122(16): 4445-4456. doi: 10.1021/acs.jpcb.8b00879

[31] Huang HH, Yang B, Ge BS, Lao J, Zhou ST, Huang F. Using self-cleavable ternary fusion pattern for efficient preparation of Bacteriorhodopsin. Process Biochemistry. 2018, 64: 206-212. doi: 10.1016/j.procbio.2017.09.024

[32] He JY, Xi LJ, Sun XZ, Ge BS, Liu DJ, Han ZX, Pu XN, Huang F. Enhanced hydrogen production through co-cultivation of Chlamydomonas reinhardtii CC-503 and a facultative autotrophic sulfide-oxidizing bacterium under sulfurated conditions. International Journal of Hydrogen Energy. 2018, 43(32): 15005-15013. doi: 10.1016/j.ijhydene.2018.06.081

[33] He H, Li S, Shi XJ, Wang XJ, Liu X, Wang Q, Guo AJ, Ge BS, Khan NU, Huang F. Quantitative Nanoscopy of Small Blinking Graphene Nanocarriers in Drug Delivery. Bioconjugate Chemistry. 2018, 29(11): 3658-3666. doi: 10.1021/acs.bioconjchem.8b00589

[34] Chi HX, Xu BM, Liu ZZ, Wei JT, Li SX, Ren H, Xu Y, Lu XW, Wang XJ, Wang XQ, Huang F. Combined thermodynamic and kinetic analysis of GroEL interacting with CXCR4 transmembrane peptides. Biochimica Et Biophysica Acta-General Subjects. 2018, 1862(7): 1576-1583. doi: 10.1016/j.bbagen.2018.04.002

[35] Zhang HT, Zhao YY, Ge BS, Huang F. Study on The Interaction of Metamorphic Protein Mad2 and Its Ligand Cdc20(121-138). Progress in Biochemistry and Biophysics. 2017, 44(3): 232-241. doi: 10.16476/j.pibb.2017.0013

[36] Yue TT, Xu Y, Li SX, Luo Z, Zhang XR, Huang F. Surface patterning of single-walled carbon nanotubes enhances their perturbation on a pulmonary surfactant monolayer: frustrated translocation and bilayer vesiculation. Rsc Advances. 2017, 7(34): 20851-20864. doi: 10.1039/c7ra01392b

[37] Yue TT, Xu Y, Li SX, Luo Z, Zhang XR, Huang F. Ultrashort Single-Walled Carbon Nanotubes Insert into a Pulmonary Surfactant Monolayer via Self-Rotation: Poration and Mechanical Inhibition. Journal of Physical Chemistry B. 2017, 121(13): 2797-2807. doi: 10.1021/acs.jpcb.7b00297

[38] Xu Y, Luo Z, Li SX, Li WG, Zhang XR, Zuo YY, Huang F, Yue TT. Perturbation of the pulmonary surfactant monolayer by single-walled carbon nanotubes: a molecular dynamics study. Nanoscale. 2017, 9(29): 10193-10204. doi: 10.1039/c7nr00890b

[39] Xu Y, Deng L, Ren H, Zhang XR, Huang F, Yue TT. Transport of nanoparticles across pulmonary surfactant monolayer: a molecular dynamics study. Physical Chemistry Chemical Physics. 2017, 19(27): 17568-17576. doi: 10.1039/c7cp02548c

[40] Wang XQ, Xiao Y, Wang C, Niu JJ, Ma J, Wang HD, Li XW, Chen X, Huang F. Hierarchical interfacial structuring of the calcareous base of the barnacle Balanus albicostatus over different length scales. Materials Chemistry and Physics. 2017, 192: 48-57. doi: 10.1016/j.matchemphys.2017.01.053

[41] Wang XQ, Wang C, Pan MH, Wei JT, Jiang FP, Lu RS, Liu X, Huang YH, Huang F. Chaperonin-Nanocaged Hemin as an Artificial Metalloenzyme for Oxidation Catalysis. Acs Applied Materials & Interfaces. 2017, 9(30): 25387-25396. doi: 10.1021/acsami.7b08963

[42] Wang XJ, Wang YA, He H, Ma XQ, Chen Q, Zhang S, Ge BS, Wang SJ, Nau WM, Huang F. Deep-Red Fluorescent Gold Nanoclusters for Nucleoli Staining: Real-Time Monitoring of the Nucleolar Dynamics in Reverse Transformation of Malignant Cells. Acs Applied Materials & Interfaces. 2017, 9(21): 17799-17806. doi: 10.1021/acsami.7b04576

[43] Ren H, Zhang Y, Guo SB, Lin N, Deng L, Yue TT, Huang F. Identifying Cu(II)-amyloid peptide binding intermediates in the early stages of aggregation by resonance Raman spectroscopy: a simulation study. Physical Chemistry Chemical Physics. 2017, 19(46): 31103-31112. doi: 10.1039/c7cp06206k

[44] Li SX, Luo Z, Xu Y, Ren H, Deng L, Zhang XR, Huang F, Yue TT. Interaction pathways between soft lipid nanodiscs and plasma membranes: A molecular modeling study. Biochimica Et Biophysica Acta-Biomembranes. 2017, 1859(10): 2096-2105. doi: 10.1016/j.bbamem.2017.08.001

[45] Lao J, He H, Wang XJ, Wang ZC, Song YZ, Yang B, Ullahkhan N, Ge BS, Huang F. Single-Molecule Imaging Demonstrates Ligand Regulation of the Oligomeric Status of CXCR4 in Living Cells. Journal of Physical Chemistry B. 2017, 121(7): 1466-1474. doi: 10.1021/acs.jpcb.6b10969

[46] He H, Liu X, Li S, Wang XJ, Wang Q, Li JQ, Wang JY, Ren H, Ge BS, Wang SJ, Zhang XD, Huang F. High-Density Super-Resolution Localization Imaging with Blinking Carbon Dots. Analytical Chemistry. 2017, 89(21): 11831-11838. doi: 10.1021/acs.analchem.7b03567

[47] Ge BS, Lin XJ, Chen Y, Wang XF, Chen HX, Jiang P, Huang F. Combinational biosynthesis of dual-functional streptavidin-phycobiliproteins for high-throughput-compatible immunoassay. Process Biochemistry. 2017, 58: 306-312. doi: 10.1016/j.procbio.2017.05.006

[48] Ge BS, Lao J, Li JQ, Chen Y, Song YZ, Huang F. Single-molecule imaging reveals dimerization/oligomerization of CXCR4 on plasma membrane closely related to its function. Scientific Reports. 2017, 7(1): 16873. doi: 10.1038/s41598-017-16802-7

[49] Ge BS, Jiang XY, Chen Y, Sun TT, Yang QX, Huang F. Kinetic and thermodynamic studies reveal chemokine homologues CC11 and CC24 with an almost identical tertiary structure have different folding pathways. Bmc Biophysics. 2017, 10: 7. doi: 10.1186/s13628-017-0039-4

[50] Zhao YY, Li LH, Wu CF, Jiang XY, Ge BS, Ren H, Huang F. Stable folding intermediates prevent fast interconversion between the closed and open states of Mad2 through its denatured state. Protein Engineering Design & Selection. 2016, 29(1): 23-29. doi: 10.1093/protein/gzv056

[51] Yue TT, Xu Y, Sun MB, Zhang XR, Huang F. How tubular aggregates interact with biomembranes: wrapping, fusion and pearling. Physical Chemistry Chemical Physics. 2016, 18(2): 1082-1091. doi: 10.1039/c5cp06511a

[52] Yue TT, Xu Y, Li SX, Zhang XR, Huang F. Lipid extraction mediates aggregation of carbon nanospheres in pulmonary surfactant monolayers. Physical Chemistry Chemical Physics. 2016, 18(28): 18923-18933. doi: 10.1039/c6cp01957a

[53] Yue TT, Tian FL, Sun MB, Zhang XR, Huang F. Inter-tube adhesion mediates a new pearling mechanism. Physical Chemistry Chemical Physics. 2016, 18(1): 361-374. doi: 10.1039/c5cp04579g

[54] Yue TT, Sun MB, Zhang S, Ren H, Ge BS, Huang F. How transmembrane peptides insert and orientate in biomembranes: a combined experimental and simulation study. Physical Chemistry Chemical Physics. 2016, 18(26): 17483-17494. doi: 10.1039/c6cp01133k

[55] Yue TT, Li SX, Xu Y, Zhang XR, Huang F. Interplay between Nanoparticle Wrapping and Clustering of Inner Anchored Membrane Proteins. Journal of Physical Chemistry B. 2016, 120(42): 11000-11009. doi: 10.1021/acs.jpcb.6b08667

[56] Wang XJ, Wang YN, He H, Chen X, Sun X, Sun YW, Zhou GJ, Xu H, Huang F. Steering graphene quantum dots in living cells: lighting up the nucleolus. Journal of Materials Chemistry B. 2016, 4(4): 779-784. doi: 10.1039/c5tb02474a

[57] Wang XJ, He H, Wang YA, Wang JY, Sun X, Xu H, Nau WM, Zhang XD, Huang F. Active tumor-targeting luminescent gold clusters with efficient urinary excretion. Chemical Communications. 2016, 52(59): 9232-9235. doi: 10.1039/c6cc03814j

[58] Ren H, Zhang GP, Lin N, Deng L, Luo Y, Huang F. Strong Fermi level pinning induces a high rectification ratio and negative differential resistance in hydrogen bonding bridged single cytidine pair junctions. Physical Chemistry Chemical Physics. 2016, 18(38): 26586-26594. doi: 10.1039/c6cp03141b

[59] He H, Wang ZC, Cheng TT, Liu X, Wang XJ, Wang JY, Ren H, Sun YW, Song YZ, Yang J, Xia YQ, Wang SJ, Zhang XD, Huang F. Visible and Near-Infrared Dual-Emission Carbogenic Small Molecular Complex with High RNA Selectivity and Renal Clearance for Nucleolus and Tumor Imaging. Acs Applied Materials & Interfaces. 2016, 8(42): 28529-28537. doi: 10.1021/acsami.6b10737

[60] He H, Wang XJ, Cheng TT, Xia YQ, Lao J, Ge BS, Ren H, Khan NU, Huang F. An Ultra-High Fluorescence Enhancement and High Throughput Assay for Revealing Expression and Internalization of Chemokine Receptor CXCR4. Chemistry-a European Journal. 2016, 22(17): 5863-5867. doi: 10.1002/chem.201600245

[61] Chi HX, Wang XQ, Li JQ, Ren H, Huang F. Chaperonin-enhanced Escherichia coli cell-free expression of functional CXCR4. Journal of Biotechnology. 2016, 231: 193-200. doi: 10.1016/j.jbiotec.2016.06.017

[62] Yue TT, Zhang XR, Huang F. Molecular modeling of membrane responses to the adsorption of rotating nanoparticles: promoted cell uptake and mechanical membrane rupture. Soft Matter. 2015, 11(3): 456-465. doi: 10.1039/c4sm01760a

[63] Yue TT, Wang XJ, Zhang XR, Huang F. Molecular modeling of interaction between lipid monolayer and graphene nanosheets: implications for pulmonary nanotoxicity and pulmonary drug delivery. Rsc Advances. 2015, 5(38): 30092-30106. doi: 10.1039/c5ra04922a

[64] Yu DY, Wang MF, Zhu GL, Ge BS, Liu S, Huang F. Enhanced photocurrent production by bio-dyes of photosynthetic macromolecules on designed TiO2 film. Scientific Reports. 2015, 5: 9375. doi: 10.1038/srep09375

[65] Wang XQ, Huang HH, Sun CH, Huang F. Structural analysis of bacteriorhodopsin solubilized by lipid-like phosphocholine biosurfactants with varying micelle concentrations. Journal of Colloid and Interface Science. 2015, 437: 170-180. doi: 10.1016/j.jcis.2014.09.007

[66] Wang XJ, Sun X, He H, Yang H, Lao J, Song YZ, Xia YQ, Xu H, Zhang XD, Huang F. A two-component active targeting theranostic agent based on graphene quantum dots. Journal of Materials Chemistry B. 2015, 3(17): 3583-3590. doi: 10.1039/c5tb00211g

[67] He H, Wang XJ, Feng ZZ, Cheng TT, Sun X, Sun YW, Xia YQ, Wang SJ, Wang JY, Zhang XD. Rapid microwave-assisted synthesis of ultra-bright fluorescent carbon dots for live cell staining, cell-specific targeting and in vivo imaging. Journal of Materials Chemistry B. 2015, 3(24): 4786-4789. doi: 10.1039/c5tb00570a

[68] Ge BS, Wang MQ, Li JQ, Liu JG, Huang F. Maltose binding protein facilitates functional production of engineered human chemokine receptor 3 in Escherichia coli. Process Biochemistry. 2015, 50(2): 285-293. doi: 10.1016/j.procbio.2014.12.001

[69] Chi HX, Wang XQ, Li JQ, Ren H, Huang F. Folding of newly translated membrane protein CCR5 is assisted by the chaperonin GroEL-GroES. Scientific Reports. 2015, 5: 17037. doi: 10.1038/srep17037

[70] Zhao XS, Wang S, Huang F. Special Topic: Biophysical Chemistry (1603-1730) Preface. Science China-Chemistry. 2014, 57(12): 1603-1604. doi: 10.1007/s11426-014-5261-1

[71] Yue TT, Zhang XR, Huang F. Membrane monolayer protrusion mediates a new nanoparticle wrapping pathway. Soft Matter. 2014, 10(12): 2024-2034. doi: 10.1039/c3sm52659c

[72] Yue TT, Zhang XR, Huang F. Molecular modeling of membrane tube pearling and the effect of nanoparticle adsorption. Physical Chemistry Chemical Physics. 2014, 16(22): 10799-10809. doi: 10.1039/c4cp01201a

[73] Yu DY, Huang GH, Xu FX, Wang MF, Liu S, Huang F. Triton X-100 as an effective surfactant for the isolation and purification of photosystem I from Arthrospira platensis. Photosynthesis Research. 2014, 120(3): 311-321. doi: 10.1007/s11120-014-9988-5

[74] Yu DY, Huang GH, Xu FX, Ge BS, Liu S, Xu H, Huang F. Effect of surfactants on apparent oxygen consumption of photosystem I isolated from Arthrospira platensis. Photosynthesis Research. 2014, 122(2): 203-213. doi: 10.1007/s11120-014-0022-8

[75] Wang XJ, Sun X, Lao J, He H, Cheng TT, Wang MQ, Wang SJ, Huang F. Multifunctional graphene quantum dots for simultaneous targeted cellular imaging and drug delivery. Colloids and Surfaces B-Biointerfaces. 2014, 122: 638-644. doi: 10.1016/j.colsurfb.2014.07.043

[76] Wang MQ, Ge BS, Yang QX, Jiang XY, Huang F. High-level production of biologically active chemokines in Escherichia coli. Process Biochemistry. 2014, 49(4): 706-714. doi: 10.1016/j.procbio.2014.01.021

[77] Song B, Sun Q, Li HK, Ge BS, Pan JS, Wee ATS, Zhang Y, Huang SH, Zhou RH, Gao XY, Huang F, Fang HP. Irreversible Denaturation of Proteins through Aluminum-Induced Formation of Backbone Ring Structures. Angewandte Chemie-International Edition. 2014, 53(25): 6357-6363. doi: 10.1002/anie.201307955

[78] Qu JB, Huan GS, Chen YL, Zhou WQ, Liu JG, Huang F. Coating Gigaporous Polystyrene Microspheres with Cross-linked Poly(vinyl alcohol) Hydrogel as a Rapid Protein Chromatography Matrix. Acs Applied Materials & Interfaces. 2014, 6(15): 12752-12760. doi: 10.1021/am5027067

[79] Yue TT, Wang XJ, Huang F, Zhang XR. An unusual pathway for the membrane wrapping of rodlike nanoparticles and the orientation- and membrane wrapping-dependent nanoparticle interaction. Nanoscale. 2013, 5(20): 9888-9896. doi: 10.1039/c3nr02683c

[80] Yu DY, Zhu GL, Liu S, Ge BS, Huang F. Photocurrent activity of light-harvesting complex II isolated from spinach and its pigments in dye-sensitized TiO2 solar cell. International Journal of Hydrogen Energy. 2013, 38(36): 16740-16748. doi: 10.1016/j.ijhydene.2013.02.114

[81] Wang XQ, Huang GH, Yu DY, Ge BS, Wang JQ, Xu FX, Huang F, Xu H, Lu JR. Solubilization and Stabilization of Isolated Photosystem I Complex with Lipopeptide Detergents. Plos One. 2013, 8(9): e76256. doi: 10.1371/journal.pone.0076256

[82] Wang MQ, Ge BS, Li RM, Wang XQ, Lao J, Huang F. Milligram Production and Biological Activity Characterization of the Human Chemokine Receptor CCR3. Plos One. 2013, 8(6): e65500. doi: 10.1371/journal.pone.0065500

[83] Qu JB, Shao HH, Jing GL, Huang F. PEG-chitosan-coated iron oxide nanoparticles with high saturated magnetization as carriers of 10-hydroxycamptothecin: Preparation, characterization and cytotoxicity studies. Colloids and Surfaces B-Biointerfaces. 2013, 102: 37-44. doi: 10.1016/j.colsurfb.2012.08.004

[84] Huang F, Johnson CM, Petrovich M, Fersht AR. Don't waste good methods on bad buffers and ambiguous data. Proceedings of the National Academy of Sciences of the United States of America. 2013, 110(5): E331-E332. doi: 10.1073/pnas.1217840110

[85] Ge BS, Li Y, Sun HX, Zhang S, Hu PJ, Qin S, Huang F. Combinational biosynthesis of phycocyanobilin using genetically-engineered Escherichia coli. Biotechnology Letters. 2013, 35(5): 689-693. doi: 10.1007/s10529-012-1132-z

[86] Yu DY, Huang F, Xu H. Determination of critical concentrations by synchronous fluorescence spectrometry. Analytical Methods. 2012, 4(1): 47-49. doi: 10.1039/c1ay05495c

[87] Leith JS, Tafvizi A, Huang F, Uspal WE, Doyle PS, Fersht AR, Mirny LA, van Oijen AM. Sequence-dependent sliding kinetics of p53. Proceedings of the National Academy of Sciences of the United States of America. 2012, 109(41): 16552-16557. doi: 10.1073/pnas.1120452109

[88] Tafvizi A, Huang F, Fersht AR, Mirny LA, van Oijen AM. A single-molecule characterization of p53 search on DNA. Proceedings of the National Academy of Sciences of the United States of America. 2011, 108(2): 563-568. doi: 10.1073/pnas.1016020107

[89] Rajagopalan S, Huang F, Fersht AR. Single-Molecule characterization of oligomerization kinetics and equilibria of the tumor suppressor p53. Nucleic Acids Research. 2011, 39(6): 2294-2303. doi: 10.1093/nar/gkq800

[90] Huang F, Ying LM, Neuweiler H, Fersht AR. Reply to Campos et al.: Direct observation versus ambiguous kinetics and thermodynamics. Proceedings of the National Academy of Sciences of the United States of America. 2009, 106(52): E140-E140. doi: 10.1073/pnas.0913321107

[91] Huang F, Ying LM, Fersht AR. Direct observation of barrier-limited folding of BBL by single-molecule fluorescence resonance energy transfer. Proceedings of the National Academy of Sciences of the United States of America. 2009, 106(38): 16239-16244. doi: 10.1073/pnas.0909126106

[92] Huang F, Rajagopalan S, Settanni G, Marsh RJ, Armoogum DA, Nicolaou N, Bain AJ, Lerner E, Haas E, Ying LM, Fersht AR. Multiple conformations of full-length p53 detected with single-molecule fluorescence resonance energy transfer. Proceedings of the National Academy of Sciences of the United States of America. 2009, 106(49): 20758-20763. doi: 10.1073/pnas.0909644106

[93] Huang F, Lerner E, Sato S, Amir D, Haas E, Fersht AR. Time-Resolved Fluorescence Resonance Energy Transfer Study Shows a Compact Denatured State of the B Domain of Protein A. Biochemistry. 2009, 48(15): 3468-3476. doi: 10.1021/bi801890w

[94] Tafvizi A, Huang F, Leith JS, Fersht AR, Mirny LA, van Oijen AM. Tumor suppressor p53 slides on DNA with low friction and high stability. Biophysical Journal. 2008, 95(1): L1-L3. doi: 10.1529/biophysj.108.134122

[95] Huang F, Settanni G, Fersht AR. Fluorescence resonance energy transfer analysis of the folding pathway of Engrailed Homeodomain. Protein Engineering Design & Selection. 2008, 21(3): 131-146. doi: 10.1093/protein/gzm069

[96] Huang F, Sato S, Sharpe TD, Ying LM, Fersht AR. Distinguishing between cooperative and unimodal downhill protein folding. Proceedings of the National Academy of Sciences of the United States of America. 2007, 104(1): 123-127. doi: 10.1073/pnas.0609717104

[97] Huang F, Nau WM. Photochemical techniques for studying the flexibility of polypeptides. Research on Chemical Intermediates. 2005, 31(7-8): 717-726. doi: 10.1163/1568567054908916

[98] Pischel U, Huang F, Nau WM. Intramolecular singlet-singlet energy transfer in antenna-substituted azoalkanes. Photochemical & Photobiological Sciences. 2004, 3(3): 305-310. doi: 10.1039/b311416c

[99] Marquez C, Huang F, Nau WM. Cucurbiturils: Molecular nanocapsules for time-resolved fluorescence-based assays. Ieee Transactions on Nanobioscience. 2004, 3(1): 39-45. doi: 10.1109/tnb.2004.824269

[100] Huang F, Nau WM. A conformational flexibility scale for amino acids in peptides. Angewandte Chemie-International Edition. 2003, 42(20): 2269-2272. doi: 10.1002/anie.200250684

[101] Gao XB, Yang JH, Huang F, Wu X, Li L, Sun CX. Progresses of derivatization techniques for analyses of carbohydrates. Analytical Letters. 2003, 36(7): 1281-1310. doi: 10.1081/al-120021087

[102] Yang JH, Huang F, Wang M, Wu X, Sun CX. Study on the molecular recognitions of calix n arenes to 2,3-diaminonaphthalene by using fluorometric technique. Spectrochimica Acta Part a-Molecular and Biomolecular Spectroscopy. 2002, 58(8): 1775-1778. doi: 10.1016/s1386-1425(01)00629-1

[103] Liu R, Yang J, Wu X, Li Z, Sun C, Huang F. Resonance Rayleigh light-scattering of thiamine hydrochloride-nucleic acids-cetyl trimethyl ammonium bromide systems and their analytical application. Journal of Trace and Microprobe Techniques. 2002, 20(3): 363-376. doi: 10.1081/tma-120006682

[104] Hudgins RR, Huang F, Gramlich G, Nau WM. A Fluorescence-Based Method for Direct Measurement of Submicrosecond Intramolecular Contact Formation in Biopolymers: An Exploratory Study with Polypeptides. Journal of the American Chemical Society. 2002, 124(4): 556-564. doi: 10.1021/ja010493n

[105] Huang F, Yang J, Hao A, Wu X, Liu R, Ma Q. The study of spectrosgraphic properties and molecular recognition of calix[n]arenes. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 2001, 57(5): 1025-1030. doi: 10.1016/S1386-1425(00)00418-2